NCI Awards HTAN 3D Imaging Grant to Fitzpatrick and Collaborators

National Cancer Institute logo

We propose a cross-disciplinary approach to quantitatively characterize the native three-dimensional architecture of human solid tumor tissue from triple negative breast cancer (TNBC) and pancreatic ductal adenocarcinoma (PDAC) patients using a combination of the state-of-the art, yet mature technologies of tissue clearing, immunofluorescence and in situ hybridization labeling, and high-resolution lightsheet fluorescence microscopy.

NIDDK Awards Program Project Grant to Develop New Therapies for Liver Fibrosis

NIDDK logo

This program project will discover and test novel compounds as potential therapeutic agents, as well as test and discover signaling pathways as potential modifiers, of liver disease due to α1antitrypsin deficiency (ATD), one of the most common genetic causes of liver disease and a frequent indication for liver transplantation.