NINDS Awards U01 for a-syn Cryo-EM

Funding Agency:  NIH / NINDS Grant No:  U01 NS110436 Title:  STRUCTURAL BIOLOGY OF ALPHA-SYNUCLEIN IN LEWY BODY DEMENTIA Abstract: Parkinson’s disease (PD) is defined pathologically by the accumulation of alpha-synuclein (Asyn) fibrils in neuronal cytoplasmic and neuritic inclusions known as Lewy bodies and Lewy neurites. The role of Asyn in the pathogenesis of PD is […]

Fitzpatrick awarded NIH HEI S10 Grant

Funding agency: NIH / OD – ORIP Grant No: S10 OD025029 Title: CRYO-FIB-SEM SYSTEM FOR THE NANOSCALE IMAGING AND MANIPULATION OF FROZEN BIOLOGICAL SPECIMENS Abstract: This proposal requests funds to acquire a Cryo-Focused Ion Beam (Cryo-FIB) microscope system in support of a diverse group of NIH-funded investigators from four different departments at the Washington University […]